|Scientific Name of this Strain
|Cupriavidus metallidurans (Goris et al. 2001) Vandamme and Coenye 2004
|IAM 14785 <- H. Kim, CH34
|Other Culture Collection No.
|IAM 14785=DSM 2839=ATCC 43123=CCUG 38400=KCTC 12956=CCUG 13724=CIP 107179=LMG 1195=JCM 21315
|Source of Isolation
|Zn decantation tank
|Locality of Source
|Country of Origin
|Plant Quarantine No.
|Animal Quarantine No.
|Former name: Ralstonia metalophila.
|Glass ampoule (L-dried)
Cupriavidus metallidurans strain CH34, (renamed from Ralstonia metallidurans and previously known as Ralstonia eutropha and Alcaligenes eutrophus) is a nonspore-forming, Gram-negative bacterium which is adapted to survive several forms of heavy metal stress. Therefore, it is an ideal subject to study heavy metal disturbance of cellular processes. This bacterium shows a unique combination of advantages not present in this form in other bacteria.
The bacteria Cupriavidus metallidurans is able to convert gold chlroride—a toxic chemical liquid into 99.9% pure gold.
- Its genome has been fully sequenced (preliminary, unnotated sequence data were obtained from the DOE Joint Genome Institute). Genome Information: PRJDB279 (NCBI BioProject).
- It is not pathogenic, therefore, models of the cell can also be tested in artificial environments similar to its natural habitats.
- It is related to the plant pathogen Ralstonia solanacearum.
- It is of ecological importance since related bacteria are predominant in mesophilic heavy metal-contaminated environments.
- It is of industrial importance and used for heavy metal remediation and sensing.
- It is an aerobic chemolithoautotroph, facultatively able to grow in a mineral salts medium in the presence of H2, O2, and CO2 without an organic carbon source. The energy-providing subsystem of the cell under these conditions is composed only of the hydrogenase, the respiratory chain, and the F1F0-ATPase. This keeps this subsystem simple and clearly separated from the anabolic subsystems that starts with the Calvin cycle for CO2-fixation.
- It is able to degrade xenobiotics even in the presence of high heavy metal concentrations.
- Finally, strain CH34 is adapted to the outlined harsh conditions by a multitude of heavy-metal resistance systems that are encoded by the two indigenous megaplasmids pMOL28 and pMOL30 on the bacterial chromosome(s).
Also it plays a vital role, together with the species Delftia acidovorans, in the formation of gold nuggets, by precipitating metallic gold from a solution of gold(III) chloride, a compound highly toxic to most other microorganisms.
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